The present invention discloses a method and system for a thermal generator set load speed changing regulation control based on a regional new energy real-time generation load. A thermal generator set load speed changing regulation control switching threshold is set according to the new energy generation capacity and the power grid operation demand in a region, and when the new energy generation load in the region is larger than the threshold, a related thermal generator set automatically completes undisturbed switching of load regulation from low-speed regulation to high-speed regulation; and when the new energy generation load in the region is smaller than the threshold, the related thermal generator set automatically completes the undisturbed switching of the load regulation from high-speed regulation to low-speed regulation. The power grid regulation capacity is enhanced, the power grid power supply quality is improved, and the capacity of the stable operation of the power grid is improved.