The invention relates to the technical field of coatings, provides a corrosion-resistant and weather-proof water-based three-dimensional paint with an imitated moire effect and a preparation method of the corrosion-resistant and weather-proof water-based three-dimensional paint, and overcomes the shortcomings that paint in the prior does not have imitated moire effect with high stereoscopic effect, and the product does not have long-time anti-corrosion property and weather resistance. The corrosion-resistant and weather-proof water-based three-dimensional paint with the imitated moire effect consists of waterborne epoxy rust inhibiting primer, waterborne acrylateintermediate coat and waterborne hydroxyl acrylic-polyurethanefinishing coat; the waterborne epoxy rust inhibiting primer consists of a component A1 and a component B1; the component A1 comprises 0-20 parts by weight of a waterborne epoxy curing agent; and the component B1 comprises the following raw materials in parts by weight: 30-70 parts of waterborne epoxy emulsion, 0.1-0.5 part of a defoamer, 0.1-1.0 part of a wetting dispersant, 0.1-20 parts of pigment, 0.1-20 parts of filler, 0.1-10 parts of rust resisting pigment, 0-1.0 part of a flash-rust resisting auxiliary agent, 0.1-0.5 part of a thickening agent, 0.5-2.5 parts of a coalescing agent and 10-30 parts of water.