The invention discloses a skin moisture measurement circuit and a skin moisture measurement instrument. The skin moisture measurement circuit comprises a first probe set, a voltage follower, a capacitor, a first resistor and a second resistor, wherein a first probe in the first probe set is controlled by a control chip to be powered on or powered off; the first end of the capacitor is electrically connected with the first end of the first resistor, and the second end of the capacitor and the second end of the first resistor are grounded; the first end of the second resistor is electrically connected with the first probe in the first probe set, and the second end of the second resistor is electrically connected with a second probe in the first probe set; the second end of the second resistor is electrically connected with the first end of the first resistor and is electrically connected with the data output end through the voltage follower. By designing the circuit, accuracy testing of skin moisture conditions can be achieved.