The invention provides an information processing method, a server, terminals and an information processing system. According to the information processing method, the server, the terminals and the information processing system, when the query information sent by a first terminal is processed, the reply information can be obtained through a second terminal corresponding to the first terminal instead of just searching reply information from a database, the condition that the server side cannot search for answers related to the query information from the database and accordingly provides invalid answers to users can be avoided effectively, and the communication quality of man-machine conversion is improved.