Disclosed is an iontophoretic device (100) for applying a cutaneous DC electrical field, the device comprising a first skin contact electrode (120) comprising a free sodium ion reservoir (122) separated from the skin (300) by a first ion-permeable barrier (124); and a second skin contact electrode (130) spatially separated from the first skin contact electrode, the second skin contact electrode comprising a free chloride ion reservoir (132) separated from the skin by a second ion-permeable barrier (134). Also disclosed is an arrangement including such device and a method of operating such device.