The invention relates to an automatic rolling and twisting type washing device of a membrane material for removing leukocytes. The washing device comprises a rack, wherein a Z-direction carrying air cylinder is mounted in the rack; the tail end of the Z-direction carrying air cylinder is in butt joint with a Y-direction carrying air cylinder; an L-shaped guide rail is arranged at the stroke end of the Z-direction carrying air cylinder and the stroke end of the Y-direction carrying air cylinder respectively; a base plate is driven by the Z-direction carrying air cylinder and the Y-direction carrying air cylinder to move to a Z direction and a Y direction along the L-shaped guide rails; a servo driving system is fixed on the base plate; a clamping mechanism is controlled and driven by the tail end of the servo driving system to rotate along an arc-shaped track. The membrane material washed by the washing device is uniform, and impurities and harmful substances in the membrane material can be effectively removed; the effect is obvious; the times of washing can be controlled by a program, and moderate washing times can be set; the opportunity of hand touch with the membrane material is reduced, so that the washing is safe, and pollution is avoided; the washing efficiency is improved, and the labor intensity is relieved.