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发明授权
CN107354126B NCAM沉默在促进ATDC5细胞的软骨细胞肥大分化中的应用 失效 - 权利终止

NCAM沉默在促进ATDC5细胞的软骨细胞肥大分化中的应用
摘要：
本发明提供了NCAM缺失在促进BMSCs细胞向肥大软骨细胞分化中的应用。通过在ATDC5细胞中转染干扰NCAM表达质粒siRNA的方法以下调内源性NCAM的表达，并将其分别进行软骨细胞分化。
摘要（英）：

The invention provides an application of NCAM deletion in promotion of differentiation of ATDC5 cells into chondrocyte hypertrophy. According to the invention, a method that plasmid siRNA which interferes NCAM expression is subjected to transfection in the ATDC5 cells is used to down-regulate the endogenous NCAM expression, and the chondrocyte differentiation is respectively carried out on the normal BMSCs and NCAM-deleted BMSCs.

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