The invention discloses a statistical analysis-based high-reliability power supply calculation system for power consumers. A statistical analysis method is used for predicting expected power failure durations of the power consumers so as to calculate possibly generated power failure loss. High-reliability investment schemes selectable for the power consumers are classified into three types: high-reliability power supply expenses are fully paid, so that the reliability of highest limit of power consumption by the consumers is ensured and the generated power failure loss is fully compensated by a power supply company; only part of the high-reliability expenses are paid, but the consumers need to bear the power failure loss in a certain range; and the high-reliability expenses are not paid, so that the consumers fully bear the power failure loss. The total costs needed to be paid by the power consumers under different schemes are compared to assist in selecting the high-reliability power supply investment scheme at relatively low cost.