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发明授权
CN107338214B 成纤维细胞及其制备方法和应用、细胞分泌液及其应用 有权

成纤维细胞及其制备方法和应用、细胞分泌液及其应用
摘要：
本发明公开了一种人胚胎干细胞来源的成纤维细胞及其制备方法和应用、细胞分泌液及其应用。该成纤维细胞可分泌多种与创伤愈合有关的细胞生长因子，可应用在制备创伤愈合药物中。该成纤维细胞的细胞分泌液中含有碱性成纤维细胞生长因子、血管内皮生长因子和转化生长因子‑β1中的一种或多种与创伤愈合有关的细胞生长因子。动物试验表明，该成纤维细胞的细胞分泌液能够促进创伤愈合，具有良好的治疗效果。该成纤维细胞及其细胞分泌液可应用在创伤愈合药物中。
摘要（英）：

The invention discloses a human embryonic stem cell derived fibroblast as well as a preparation method and an application thereof, cell secretion fluid and an application thereof. The fibroblast, which can secrete a plurality of cell growth factors which are related to wound healing, can be applied to preparation of wound healing medicines. The cell secretion fluid of the fibroblast consists of one or more cell growth factors, which are related to the wound healing, in basic fibroblast growth factors, vascular endothelial growth factors and transforming growth factors-[beta]1. Animal experiments show that the cell secretion fluid of the fibroblast can promote wound healing and can take an excellent therapeutic effect. The fibroblast and the cell secretion fluid thereof can be applied to the wound healing medicines.

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