The invention discloses a clinical grading diagnosis and treatment data management system for diabetic retinopathy patients, and belongs to the technical field of computer database software application. A database module is used for storing all information data and classifying and managing information, and is used for compressing, transmitting and reading the information data by means of information security confidentiality technology. A clinical diagnosis and treatment module is used for providing a complete clinical diagnosis and treatment process and conducting follow-up records according to a follow-up period. A clinical follow-up module is used for providing clinical specialized medical service and accumulating an original scientific research data platform. A patient management module is used for guiding the patients to participate in the clinical diagnosis and treatment process, evaluating the patient eye care present situation, including eye care present situation questionnaires and life quality records, and conducting supervision on self-management in the patient diagnosis process. A knowledge base module is used for storing a guide of current diabetic retinopathy treatment and relevant knowledge of the patient questionnaires, so that medical workers standardize their diagnosis and treatment activities according to the guide and provide the specialized medical service for the patients.