The invention relates to a vertical mixing and stirring station, and belongs to the material mixing field. The station comprises supports, a mixing tank is arranged on the supports, and the mixing tank is circular in shape; a buffering mechanism is arranged between the supports and the mixing tank, the supports are a plurality of groups of supports, and a reinforcement is transversely arranged between every group of the supports; a cover plate is arranged above the mixing tank, the mixing tank is provided with a main shaft from top to bottom, the upper end of the main shaft is fixed on the cover plate through a fixing bearing, a supporting mechanism is arranged below the mixing tank, the lower end of the main shaft is fixed on the supporting mechanism through a fixing bearing, the main shaft is cooperatively provided with a connecting piece, the connecting piece is cooperatively provided with blades, the blades are arranged surrounding the main shaft, the blades comprise large blades and small blades, the large blades are fixed on a position, far from the main shaft, of the connecting piece, the small blades are fixed on a position, close to the main shaft, of the connecting piece, angle adjusting mechanisms are respectively arranged between the large blades and the connecting piece and between the small blades and the connecting piece, and the angle adjusting mechanisms are cooperatively provided with a cleaning device in the mixing tank. The station can highly-efficiently mix and stir materials, and can improve the stirring efficiency and shorten the stirring time through the cooperative arrangement of the large blades and the small blades.