The invention provides an adjust and control method and device of a power supply and a computer readable storage medium. The method comprises the steps that power source values of current loads and the preset standard power supply values of standard direct current power supply modules are obtained; according to the power supply values and the standard power supply values, the number of the standard direct current power supply modules required by current load work is calculated; according to the power supply values, the standard direct current power supply modules of the number are in series and/or parallel connection, and thus the direct power supply values equal to the power supply values are outputted to provide power for the current load work. In this way, the power supplying mode is safe and reliable, and the adjust and control device provides a safe and stable household electricity environment for users; under the condition that no power supply needs to be added additionally, the direct current power supplying power supplies of different specifications can be obtained, the electricity demands of different loads are met, the flexibility of power supply configuration is improved, and the electricity cost is lowered.