The invention belongs to the technical field of membranes and provides a piperazine functional polyphenyl ether alkaline anion-exchange membrane and a preparation method thereof. The method for preparing the piperazine functional polyphenyl ether alkaline anion-exchange membrane comprises the following steps: carrying out an acylation reaction on polyphenyl ether, condensing with N-alkylpiperazine, and functionalizing, thereby obtaining the polyphenyl ether membrane material containing a piperazine functional group, shown as a formula I. According to the alkaline anion-exchange membrane prepared by the method disclosed by the invention, the hydroxyl ion conductivity reaches 128 mS cm<-1> at the temperature of 80 DEG C; and after the membrane is soaked in a 1M NaOH solution at the temperature of 60 DEG C, the hydroxyl ion conductivity and the ion-exchange capacity are not decreased along with the increase of soaking time. The performance of the piperazine functional polyphenyl ether alkaline anion-exchange membrane disclosed by the invention is far higher than that of the currently reported alkaline anion-exchange membrane.