The invention discloses a zirconium oxide powder, as well as a product and a preparation method thereof. The zirconium oxide powder is characterized by comprising ZrO2,HfO2 and MxOy serving as main components, wherein MxOy is a metal oxide, and the content of the MxOy is less than or equal to 15 molar percent of the main component; M is selected from one or more of yttrium, calcium, magnesium, cerium, praseodymium, vanadium, molybdenum and titanium; the main component is over 90 mass percent of the zirconium oxide powder; each of other metal oxides, except the main component, is less than or equal to 0.01 mass percent of the zirconium oxide powder. The method comprises the steps of performing solid-liquid separation under a specific pH value for two times. A pressed body which is prepared by the zirconium oxide powder is high in purity and high in mechanical property, is low in radioactivity when being used for preparing a ceramic material, and can be used as a biological ceramic material, such a false tooth and an artificial bone.