The invention discloses a preparation method of an anti-oxidative nanometer cuprous chloride catalyst, and an application of the catalyst in the catalytic degradation of organic pollutants. The preparation method comprises the following steps: dissolving a soluble copper salt in distilled water, sequentially adding ammonia water and a phenol solution to the above obtained stirred and uniformly mixed solution, adding an antioxidant, stirring and uniformly mixing all above substances to form a reaction precursor, transferring the reaction precursor into a reaction kettle, carrying out a reaction at 120-180 DEG C for 10-26 h, coagulating the obtained reaction product to form cuprous chloride on the inner wall of the reaction kettle, and washing and drying the cuprous chloride to obtain anti-oxidative cuprous chloride nano-particles. The prepared anti-oxidative cuprous chloride nano-particles can be used to catalyze the sodium borohydride degradation of the organic pollutants. The preparation method for synthesizing the cuprous chloride through using a hydrothermal technology has the advantages of simplicity, easiness in control, low cost and high operability. The prepared anti-oxidative nanometer cuprous chloride has the advantages of very high specific surface area, very good oxidation resistance, good catalysis performance and good reusability, and can be well used to catalyze the sodium borohydride degradation of the organic pollutants.