The invention discloses a flexible transparent conductive electrode based on a polyimide substrate. The flexible transparent conductive electrode based on the polyimide substrate comprises the polyimide substrate, an infiltrating layer, a metal layer, a metal mesh layer and an antireflection layer. The adhesion between the metal stack layer and the metal mesh on the substrate is ensured by setting the infiltrating layer between the PI substrate and the metal stack layer, therefore, the adhesion of the metal mesh is good, and the low square resistance of the electrode is ensured; so that the metal stack layer can be made into ultra-thin thickness, and then the good light transmittance is achieved. The layers of the electrode structure disclosed by the invention are coordinated with one another to form a complete technical scheme; therefore, the electrode light transmittance of the PI substrate disclosed by the invention is high, and the square resistance is low; and when the flexible transparent conductive electrode based on the polyimide substrate is connected with a device, the light transmittance is improved and the short circuit of the device is avoided because of the setting of the antireflection layer.