The invention relates to the field of medical instruments and particularly relates to a closure device of a laparoscopic purse-string device. The closure device comprises a connector and a jaw which are connected, wherein the connector is provided with a runner; the jaw is provided with two staple cartridge covers; one end of each staple cartridge cover is connected with the runner and can rotate around the runner to achieve the opening and closing of the jaw; a plurality of suturing mechanisms are arranged in each staple cartridge cover; and each suturing mechanism comprises a suturing nail, a staple cartridge, a nail push sheet, a leaf spring, two rotating feet and two push feet. Compared with the prior art, the functions of traditional purse-string forceps can be achieved, and the closure device is suitable for a small intestine operation, a colon operation, a rectum operation, an esophagus operation and a stomach operation, is convenient to use and finer in structure, is capable of providing enough power for suturing, and swinging at a certain angle, is capable of being freely opened and closed and providing convenience for operation, and further meets the development of a minimally invasive technology.