The invention discloses a sea sand desalination-based processing process. The sea sand desalination-based processing process comprises the following steps that (1) an offshore sea sand collecting ship collects sea sand in an offshore collecting area; (2) after being collected, the sea sand is transported to an offshore desalination ship; (3) a transport ship transports fresh water to a desalination device of the offshore desalination ship to perform desalination on the sea sand; and (4) after desalination is finished, the sea sand is transported by the transport ship to a land sea sand finished product stacking area to be treated by a non-shore-based production line, and finished sand is stacked on a shore or directly sold on the shore. As a treatment process is added in a sea sand collecting and transporting process, and compared with shore-based treatment, the treatment process of the sea sand desalination-based processing process is advanced, process steps are reduced, the shore-based transshipment amount is reduced, shore-based treatment emission is reduced, on the premise that the quality is guaranteed, the process flow of sea sand desalination treatment is shortened, the whole efficiency of sea sand desalination treatment is improved, and cost of a technical scheme is reduced; and as the fresh water can be provided through transshipment after the transportation ship takes the fresh water from a fresh water area, land pollution discharge is reduced, land occupation area is reduced, and affection to sea sand desalination treatment by field limitation is avoided.