The invention provides a fermentation production method for efficiently extracting flavones from ginkgo leaves. The fermentation production method comprises the following steps: cleaning ginkgo leaves, crushing till 20-100 meshes, and mixing the ginkgo leaves with water, wherein the water accounts for 40-60%; putting the mixture into a fermentation tank, sterilizing at a temperature of 121 DEG C, and performing steam explosion; further adding aspergillus niger for fermentation, further adding a mixed enzyme liquid which accounts for 2-5% of a reaction substrate, performing reaction for 3-6 hours at 25-30 DEG C, further adding 1% of protease, and performing reaction for 3-4 hours at 25-30 DEG C; heating for 10 minutes to 95 DEG C, further adding an extraction agent to extract flavones, centrifuging for 20 minutes at 12000g, concentrating supernate, performing digestion extraction with ethanol, collecting an ethanol eluant, concentrating, and performing freeze-drying, so as to obtain a product. The fermentation production method provided by the invention is simple in process and high in extraction efficiency, moreover, toxic or harmful organic solvents are not used in the process, so that a final product is free of organic solvent residue and is safe to use by people.