The invention discloses a method and station-level comprehensive monitoring system for synchronizing power monitoring information. The method comprises the steps of reading basic information in a configuration file by the station-level comprehensive monitoring system during starting, wherein the basic information comprises an incidence relation between a station and a substation; acquiring a basic information request information sent from a comprehensive automatic system of the substation by the station-level comprehensive monitoring system; and sending a first synchronization message to the comprehensive automatic system of the substation by the station-level comprehensive monitoring system so that the incidence relation between the station and the substation is read by the comprehensive automatic system of the substation to complete system starting, wherein the first synchronization message comprises the incidence relation between the station and the substation. By the method, resource uniformity of the station-level comprehensive monitoring system and the comprehensive automatic system of the substation is achieved, so that the system is convenient and rapid to implement, and the system efficiency is improved.