The invention relates to a syringe easy in medicine blending and a working method of the syringe. The syringe comprises a cylinder and a push rod, wherein a piston plate is arranged at an end part ofthe push rod; the piston plate is in airtight reciprocation sliding along the inner wall of the cylinder; a limiting plate is fixedly arranged on the inner wall of the cylinder; the push rod penetrates through the limiting plate and can be pulled in a reciprocation manner relative to the limiting plate; the cylinder is further internally provided with a stirring rod; the stirring rod is parallel to the push rod; a stirring blade is arranged at one end penetrating through the piston plate, of the stirring rod; a shift piece is arranged at the other end penetrating through the limiting plate, ofthe stirring rod; a spring is connected between the shift piece and the limiting plate; the stirring rod and the piston plate are kept in airtight connection; and the stirring rod can be pulled in areciprocation manner relative to the push rod. The syringe is novel and unique in structure, medicine blending procedures can be effectively simplified, the medicine blending and injection efficiencycan be greatly improved, the working pressure of medical operators can be alleviated, and meanwhile, medicine waste, medicine residues and pollution can be effectively prevented.