The invention discloses a novel pillowcase, which comprises a pillowcase body, wherein a pillow towel is connected to one side of the pillowcase body; the pillow towel and the pillowcase body are connected by virtue of detachable connecting mechanisms which are arranged at left and right sides; the pillow towel is of a double-side structure, wherein the front side of the pillow towel is a suede layer and the back side of the pillow towel is a cold mat layer; a warm-keeping layer is arranged between the front side and the back side of the pillow towel; traditional Chinese medicine health-care bags are arranged at two ends of the pillow towel main body; a massaging mat is arranged between the traditional Chinese medicine health-care bags; the massaging mat and the traditional Chinese medicine health-care bags are movably connected; and temperature-controlled alarms are arranged in the traditional Chinese medicine health-care bags. The pillowcase provided by the invention is reasonable in structure, convenient to clean, clean and sanitary, safe to use and beneficial for human health, and the pillowcase is capable of reducing reproduction of bacteria; the pillow towel, which is connected to a pillow, is easy to keep and store; cold and warm sides of the pillow towel can be selected in accordance with different temperatures; meanwhile, the pillowcase has a plurality of functions such as massaging, medicine health care, calming heart and promoting sleep, temperature induction and the like; and the pillowcase is simple in structure, low in cost, and convenient and practical.