The invention provides a peristaltic pump for a clothes ironing setting machine, and belongs to the technical field of clothes production and selling. The technical problem that an existing clothes ironing setting machine contaminates clothes is solved. The clothes ironing setting machine comprises a setting machine body, the peristaltic pump is arranged on the setting machine body and is provided with a water inlet connector, a water outlet connector, a motor, a pump body and a hose, the motor is provided with an output shaft of a hollow structure, a middle shaft is fixedly arranged in the output shaft, a lubricating cavity is formed between the middle shaft and the output haft, an impeller is fixedly disposed at one end of the output shaft, and the impeller is composed of a plurality of evenly distributed blades. A sliding groove is formed in the inner wall of the body, the hose is embedded in the sliding groove, rollers capable of freely rotating are arranged at the outer ends of the blades, the rollers abut against the hose so as to tightly press the hose on the inner wall of the sliding groove, and an inlet and an outlet of the hose are connected with the water inlet connector and the water outlet connector respectively. The peristaltic pump has the advantages of being free of pollution, high in efficiency and the like.