The invention discloses a clear production method for a zhongshengmycin parent drug. The method comprises the recycling of fermenter discharge washing water, spray tower washing water, spray dedusting wastewater in a spray process, washing water for membrane systems including a ceramic membrane system and a nanofiltration membrane system, nanofiltration membrane system filtering permeate and so on from a zhongshengmycin parent drug production process as water for preparation of a fermentation medium for a zhongshengmycin fermentor or a fermenter supplemented medium. The method reduces the discharge of NH3-N wastewater with high concentration and high COD during the production process to achieve energy saving, emission reduction and clean production. The method does not reduce the level of zhongshengmycin fermentation production and the product quality of the zhongshengmycin parent drug and reduces the loss of the product and the use of water resources, meanwhile the method reduces the labor intensity of employees, saves manpower and material resources, enhances the environment-friendly compatibility of the zhongshengmycin parent drug production, and has good economic and social benefits.