The invention provides high-compression-ratio waste compression and transit equipment. The equipment comprises a waste collecting box arranged underground and a waste transit and storage box arranged on the ground. A waste upward compression device is arranged between the waste collecting box and the waste transit and storage box. A discharging device is arranged in the waste transit and storage box. A waste slot is formed in the top of the waste collecting box. A sewage collecting well is arranged beside the waste collecting box. Water leaking holes are formed in the wall of a conveying channel and the wall of a compression channel. The water leaking holes communicate with the sewage collecting well. The high-compression-ratio waste compression and transit equipment has the beneficial effects that (1) the waste collecting box is installed in an underground foundation pit, a top sealing cover plate is in seamless butt joint with the bottom of the waste collecting box, and accordingly sewage and undesirable odor are effectively prevented from being discharged; (2) the volume of the waste transit and storage box is designed to be variable according to the waste amount of a covering area of a waste transfer station, the equipment volume is sufficiently utilized, and the construction investment of the waste transfer station is reduced; and (3) the size of waste is sufficiently decreased through the high compression ratio, and accordingly the waste transfer cost is substantially reduced.