The invention relates to the technical field of shoe soles, in particular to a shoe sole with massage and magnetic therapy functions. The shoe sole is characterized in that a leather structure is arranged on the upper surface of a waterproof layer in a clinging manner, the thickness of the leather structure is smaller than that of the waterproof layer, a magnetic therapy layer is further arranged on the upper surface of the leather structure, and a cushion structure layer clings to the upper portion of the magnetic therapy layer; the magnetic therapy layer comprises an upper layer structure and a lower layer structure, the upper layer structure is sewed and connected with the lower layer structure, inner cavities of the upper layer structure and the lower layer structure are filled with cotton products, arc-shaped grooves are formed in the opposite sides of the upper layer structure and the lower layer structure, through holes are communicated with the tops of the arc-shaped grooves of the upper layer structure, magnetic balls are arranged in the arc-shaped grooves, and the radius of each magnetic ball is larger than the sum of the length of each through hole and the thickness of the cushion structure layer. The shoe sole has the advantages that real-time massage and magnetic therapy can be constantly carried out on the foot sole of a wearer, the health of the internal organs in the body of the wearer can be adjusted, and accordingly the balance of the endocrine system of the body of the wearer can be regulated.