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发明授权
CN106662589B 先兆子痫的早期检测 有权

先兆子痫的早期检测
摘要：
本发明提供了非侵入性测定以可靠地鉴定患有或有倾向发生先兆子痫(PE)的女性。所述方法包括测量从对象获得的测试样品中膜联蛋白A2(ANXA2)的水平；以及当所述测试样品中ANXA2的水平相对于对照样品降低时，鉴定所述对象为患有先兆子痫或发生先兆子痫的风险提高。还提供了治疗鉴定为患有PE或发生先兆子痫风险提高之对象的方法。
摘要（英）：

The invention provides non-invasive assays to reliably identify women who have or are predisposed to developing preeclampsia (PE). The method comprises measuring a level of annexin A2 (ANXA2) in a test sample obtained of a subject; and identifying the subject as having preeclampsia or at an increased risk of developing preeclampsia when the level of ANXA2 in the test sample is decreased in relation to a control sample. Methods to treat subject identified as having PE or at an increased risk of developing preeclampsia are also provided.

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