The invention relates to the field of medical equipment, in particular to an automatic filling machine of medical bottles. The automatic filling machine comprises a rotating plate arranged on a supporting seat. A bottle body conveying device matched with the rotating plate is arranged on the left side of the rotating plate. A medicine filling device matched with the rotating plate is arranged on the rear side of the rotating plate. Bottle clamping slots matched with bottle bodies are uniformly formed in the rotating plate. The bottle bodies are matched with a medicine outlet of the medicine filling device. The rotating plate, the bottle body conveying device and the medicine filling device are connected to a controller. According to the automatic filling machine of the medical bottle, the rotating plate is arranged in the machine, the bottle clamping slots matched with the bottle bodies are formed in the rotating plate, each empty bottle body conveyed through the bottle body conveying device is clamped through the corresponding bottle clamping slot, moved below the filling device through rotating of the rotating plate and moved away after filling, and a next empty bottle body is supplemented. Continuity of filling is improved greatly, and accordingly the filling efficiency is improved.