The invention discloses a combined multi-sealing clamping sleeve comprising a clamping sleeve main body, an inner pipe accommodating hole, an outer pipe accommodating groove, an internal threaded surface, an external threaded surface, a first sealing groove, a first sealing ring, a second sealing groove, a second sealing ring, an inner step ring, a third sealing ring, a third sealing groove and a fourth sealing ring. By using the combined multi-sealing clamping sleeve, a clamping sleeve joint is enabled to directly have a multi-sealing effect, and additionally providing a sealing device is not needed; and the combined multi-sealing clamping sleeve is integrally mounted and is high in matching ability, good in working state, reasonable in structure, convenient to mount and beneficial to popularization and application, and faults such as leakage by mistake are not easily caused.