The invention provides a pressure-balance self-cleaning filter including an end cover, a piston, a core rod, a casing, a filter core, a piston spring and a core rod spring; the end cover is located at the top and is connected with the lower-part casing, and the piston, the piston spring, the core rod, the filter core and the core rod spring are arranged between the end cover and the casing from top to bottom successively; the top of the end cover is provided with a liquid inlet hole, and the piston is provided with a liquid inlet hole and a leakage hole; the upper part of the core rod is provided with a liquid inlet hole, the middle of the core rod is provided with a seal, the lower part of the core rod is provided with a liquid outlet hole, a plurality of core rod flushing holes are formed between the core rod liquid inlet hole and the core rod seal, and the core rod liquid inlet hole, the core rod liquid outlet hole and the core rod flushing holes communicate with each other; the middle part of the casing is provided with a blow-down hole, and the bottom of the casing is provided with a liquid outlet hole. Pressure balance can be generated with the help of a self structure and filtered media under a condition without external addition of a power device; through the inner and outer medium pressure difference of the filter core, the filter core is automatically cleaned; and moreover, the pressure-balance self-cleaning filter is flexible in size and wide in application scope.