The invention discloses a synthesis process of a fluoroglycofen active compound. The fluoroglycofen active compound comprises 5-13 parts of ethyl acetate, 20-43 parts of acifluorfen, 10-15 parts of emulsifier, 15-19 parts of methyl oleate, 3-8 parts of caustic soda flake, 7-10 parts of paraquat, 8-15 parts of phenyl phenol polyoxyethylene ether and 30-50 parts of deionized water. By mixing ethyl acetate, acifluorfen, emulsifier, methyl oleate, caustic soda flake, paraquat, phenyl phenol polyoxyethylene ether and deionized water together according to a certain proportion, chemical reaction occurs, so that saving of time, quick action and high efficiency during dissolving are realized; a herbicide after being absorbed by weed can directly give play to effect to thoroughly kill the weed, so that convenience is brought to people's work.