The invention discloses a water resource configuration method based on a general rule framework set and belongs to the water resource configuration field. Through abstracting present actual configuration rules, summarizing general rule frameworks to form a framework set and establishing a water resource configuration simulation model which is applied to specific basins or areas, water resource configuration instantiation of a water resource configuration simulation model is carried out. The method is advantaged in that a problem of region restrictions existing in a water resource configuration simulation model in the prior art is solved; generalization of the water resource configuration simulation model is realized, and flexibility and applicability are improved; the general rule framework set is provided, customized rule framework analysis is provided for special regions, so the water resource configuration model is enabled to have strong development property; a current path of each water resource configuration process can be precisely described in detail, each link of water resource configuration is controlled, and a current trend can be intelligibly mastered; flexible boundary condition interfaces can be provided, and coupling with other models is convenient.