The invention provides a method for loading an application based on a browser. The method for loading the application based on the browser comprises sending a domain name request to a server or cloud, and receiving response information including configuration information corresponding to the domain name, wherein the domain name corresponds to an application; searching a plug-in in the system based on the response information, wherein a parameter of the plug-in is set and is variable; assigning a value to the parameter in dependence on the configuration information and loading the assigned plug-in; and calling an application stored in the server or cloud by means of the plug-in in order to operate the application in the webpage. According to the invention, applications compiled by means of a predetermined interface can be loaded in almost all browsers (as long as browsers exploited based on the IE kernel, for example IE6-IE11, Webkit and the like), and the compatibility is high.