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发明授权
CN106399532B 一个影响猪生长和PRRSV抗性的SLA-DRB1启动子区分子标记及其引物和应用 有权

一个影响猪生长和PRRSV抗性的SLA-DRB1启动子区分子标记及其引物和应用
摘要：
本发明公开了一个影响猪生长和PRRSV抗性的SLA‑DRB1启动子区分子标记及其引物和应用。一个影响猪体重和PRRSV抗性的分子标记，位于猪SLA‑DRB1基因启动子区‑30位点，且具有C/T多态性，CC型体重高于CT型和TT型，CC型仔猪感染PRRSV后血液中PRRSV相对量低于CT型和TT型。一种筛选高生长性状和具有PRRSV抗性的猪品系的方法，包括检测猪SLA‑DRB1基因启动子区‑30位点的多态性，选择CC型个体留种。该多态位点可用于猪生长和PRRSV抗性的辅助选择，提高选择的准确性。
摘要（英）：

The invention discloses an SLA-DRB1 promoter region molecular marker affecting pig growth and PRRSV resistance as well as a primer thereof and an application thereof. The molecular marker affecting pig weight and PRRSV resistance is positioned at the site 30 of a pig SLA-DRB1 gene starter region, and has C/T polymorphism; CCT type body weight is higher than CT type body weight and TT type body weight; and after CC type piglets are affected with PRRSV, relative content of PRRSV in blood is lower than that of PRRSV of the CT type and the TT type. A method for screening a pig system with high growth characters and PRRSV resistance comprises the steps of detecting polymorphism of the site 30 of the pig SLA-DRB1 gene starter region, and selecting CC type individuals to reserve seeds. The polymorphic site can be used for auxiliary selection for pig growth and PRRSV resistance, so that selection accuracy is improved.

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