The invention relates to a small-size color change indication device. The small-size color change indication device comprises: an indication layer, a base layer and a substrate layer, wherein the indication layer comprises a carbon dioxide sensitive indication layer, an oxygen sensitive indication layer, a hydration color change indication layer and a dehydration color change indication layer; a containing body for separating gas is formed by the substrate layer and the base layer; the substrate layer is made of a transparent material; the indication layer is contained in a sealed space of the containing body; each of the substrate layer and the base layer is of a whole piece type structure; at least one of the substrate layer and the base layer can be punctured by a sharp tool to form an air vent, so that the containing body is communicated with the outside. The small-size color change indication device provided by the invention has a relatively simple structure and miniaturization is facilitated.