The invention discloses a brain drainage bottle fixing frame and relates to the field of medical equipment. The brain drainage bottle fixing frame comprises a fixing frame base and a fixing frame body, wherein the fixing frame base is equipped with universal wheels; a fixing rod provided with hooks at the top end is inserted into the fixing frame body, a zero-point scale is arranged at a joint end of the fixing rod with the fixing frame body, an upper fixing ring and a lower fixing ring are arranged at the end, close to the hooks, of the fixing rod, and a graduated scale is arranged on a rod body of the fixing rod; a fixing frame zero-point flange and a fixing knob are arranged at the end, connected with the fixing rod, of the fixing frame body, and a zero-point scale groove and a rotary shaft are arranged on the zero-point scale; brakes are arranged on the universal wheels. The brain drainage bottle fixing frame can solve the problems that a drainage effect and intracranial pressure of a patient are affected by fixing deviation of a brain drainage bottle and the nursing and medical workload is increased.