The invention relates to the technical field of tissue culture, in particular to a culture medium for coriaceous euonymus tissue culture and a method thereof. The culture medium for coriaceous euonymus tissue culture comprises an initial culture medium, a proliferation culture medium and a rooting culture medium. The culture medium can remarkably improve the survival rate and transplanting survival rate of the initially cultured coriaceous euonymus, the initiated culture survival rate is improved from existing below 30% to 85%, and the transplanting survival rate of seedlings is improved from existing 50% to existing above 90%. By utilization of the plant tissue culture method, the problems of long period and low reproduction rate of a traditional coriaceous euonymus reproduction mode are solved, a rapid coriaceous euonymus reproduction and culture system is formed, and industrialized seedling raising can be achieved.