The invention provides a prevention and treatment method for anthrachose of grapes which is characterized by comprising following steps:1. a mixed solution of 0.3%-0.5% sodium pentachlorophenate and 4-grade lime sulphur is sprayed before germination; first chemical spray is performed during growing period when new shoot are as long as 15cm, chemical spray is performed 3 to 5 days before flowering and 3 to 5 days after fading; chemical spray is performed once every half month from young fruit stage and 3 to 5 times of chemical spray is continuously performed, chemical spray is performed once every 7 to 10 days in rainy days; 2. diseased ears and diseased fruits are removed and picked up during growing period, and fallen leaves and branches are cleaned up; diseased branches, diseased leaves, diseased fruits and aged bark in trunks and veins are cleaned up after fruit harvest and burned concentratedly; 3. seedlings are soaked in 3% to 5% cupric sulfate solution for 3 to 5min before plantation and then disinfection is performed; drainage ditches are dug around the vineyard and among rows. The prevention and treatment method for anthrachose of grapes of the invention is convenient and easy to perform and can effectively increase the output and quality of grapes, and is conducive to a wide range of promotion and application.