The present invention provides a control circuit and a control method for a switch circuit and a switching-mode power supply circuit. The control method comprises following steps: detecting an output voltage or an output current, and adjusting an upper limit value and a lower limit value of an inductor current according to a result of comparing the output voltage or the output current with the corresponding reference; and sampling the inductor current, and controlling a main switch transistor in the circuit to be switched off when a sampling current rises to the upper limit value, and controlling the main switch transistor to be switched on when the sampling current drops to the lower limit value. In the present invention, the inductor current is fast in response without overshoot, the output voltage drops very little, there is no overshoot in a process of voltage recovery, and circuit transient response is fast.