The invention discloses a latex-enhanced immunoturbidimetry kit for detecting SOD in serum. The kit comprises a reagent R1, a reagent R2 and a calibrator, the reagent R1 comprises a buffering solution, an electrolyte, a reaction enhancer, a stabilizer and a preservative, the reagent R2 comprises SOD antibody sensitization resistant latex particles, a buffering solution, an electrolyte, a stabilizer, a surfactant and a preservative, and the calibrator comprises a buffering solution, a stabilizer, a preservative and SOD recombinant protein. By utilizing polyclonal antibody to coat latex particles and combining the advantages of latex-enhanced immunoturbidimetry, the kit has the advantages of high sensitivity, high accuracy, wide linear range and high detection throughput and is highly suitable for clinical diagnosis application.