The invention discloses a universal prefabricated GIS hollow-box foundation, a hoisting method and an embedded part layout method. The universal prefabricated GIS hollow-box foundation is formed by fixedly connecting a plurality of GIS foundation modules together, and each GIS foundation module is an integrated octagonal prism box of a cavity structure. GIS universal embedded parts are arranged on the upper surface of the universal prefabricated GIS hollow-box foundation. According to the universal prefabricated GIS hollow-box foundation, the hoisting method and the embedded part layout method, small components, composed of multiple parts, of the GIS foundation are unified in design dimension, and standardization is achieved, so that the purpose of universality is achieved, and the problem of uncertainty of preservation of pre-embedded parts for future enlargement is solved.