The invention relates to the technical field of wood surface modification, in particular to a method of preventing a furniture wood from breeding worms. The method comprises the following steps: polishing the surface of the furniture wood by abrasive paper, putting the furniture wood in a sealed vessel, heating the sealed vessel to enable the temperature in the sealed vessel to be 100-200 DEG C, meanwhile, adding an aqueous boride solution, carrying out vacuum-pressure impregnation, then soaking the furniture wood in melamine modified low-molecular weight urea-formaldehyde resin for 1-2h, taking out the furniture wood for airing, then coating a waterborne epoxy resin coating on the surface of the furniture wood with the coating thickness being 0.04-0.06mm, and finally, leaving the furniture wood at room temperature for 10-15 days. By using the method to treat the wood, the size stability is improved, suncrack caused by being heated after a long time is prevented, the physical and mechanical properties are improved, the service life of the wood is prolonged, environment is protected without pollution, and furniture prepared by adopting the wood is not damaged by the worms after being used for a long time.