The present invention is directed to eliminate diagonal weave lines that appear on the surface of a fabric due to warp knuckles. The present invention is also directed to provide an industrial two-layer fabric that prevents transfer marks from forming by suppressing the separation or aggregation of adjacent wefts, which has occurred in conventional pattern structures, and has excellent surface smoothness and running stability. An industrial two-layer fabric includes an upper layer fabric including upper side warps and upper side wefts and a lower layer fabric including lower side warps and lower side wefts, and the upper layer fabric and the lower layer fabric are bound by warps that function as binding yarns. In the industrial two-layer fabric, warp knuckles are formed on a surface side, and each warp knuckle is formed by allowing a warp to pass over a single upper side weft; in a shaft adjacent to the warp knuckle, at least two other warp knuckles are arranged in a diagonal direction in a planar view; and the warp knuckles are sequentially arranged in such a way as to form a herringbone pattern on a surface layer side of the fabric.