The invention provides a little yellow croaker female fish and large yellow croaker male fish crossbreeding method, and belongs to the technical field of aquaculture seawater fish larval breeding. The method comprises the following steps of 1, parent selection and culture; 2, artificial hasten parturition and insemination: a, artificial hasten parturition; b, artificial egg extrusion and semen collection; c, artificial dry process and insemination; d, egg washing; 3, larval breeding management; 4, larva and young fish culture. The method has the advantages that the little yellow croaker and large yellow croaker crossbreeding is performed; new varieties with high growth speed and excellent quality can be cultured; in addition, the fertility rate of the new varieties can reach 65 percent or higher; the hatching rate reaches 92 percent or higher; important application values are realized on the production; the health development of the aquaculture industry in China is promoted.