The invention discloses a 3D-priniting extracorporeal-assisted biopsy/positioning device. The biopsy/positioning device is formed by 3D printing. The 3D-priniting extracorporeal-assisted biopsy/positioning device comprises a central positioning module, in which a needle-feeding hole duct used for feeding a puncture needle is arranged. The surface of the central positioning module is provided with a first clamping slot. The 3D-priniting extracorporeal-assisted biopsy/positioning device further comprises an antenna with one end having a first clamping pin in snap joint with the first clamping slot and with the other end having a second clamping pin, a fixing foot stand comprising a base and support feet arranged on the base. The support feet and a plane where the base is located are arranged at certain angle. One end, away from the base, of the support feet is provided with a second clamping slot. The second clamping slot is in snap joint with the second clamping pin. The 3D-priniting extracorporeal-assisted biopsy/positioning device is broad in application scope, short in operation time and helps relive pains of a patient and achieves prices positioning and puncture biopsy of preoperative lumps.