A manufacturing and use method of a turbine type manual drive unit of a wheelchair are disclosed. The turbine type manual drive unit comprises cranks, turbine cases and friction wheels, which are connected together, wherein the friction wheels are installed on the output shafts of the turbine cases, the friction wheels are in close contact with the tyre sidewalls of driving wheels of the wheelchair, the cranks are connected to the worms of the turbine cases, and suspension ring screws respectively penetrate through the cranks and the output shafts to fix the cranks and the output shafts. A disabled person can hold two cranks with two hands during use. The driving wheels of the wheelchair are driven to rotate through the friction wheels by rotating the cranks, thereby realizing moving of the wheelchair.