The invention discloses a fingerprint signature electrical locking system comprising a housing and a power supply. The front surface of the housing is provided with a liquid crystal screen, a fingerprint acquisition window, and an operation button. A fingerprint module, a control module, a display module, a locking mechanism, and a single-chip microcomputer are disposed in the housing. The output end of the fingerprint module and the output end of the control module are connected with two I/O input ends of the single-chip microcomputer, and one I/O output end of the single-chip microcomputer is connected with the input end of the display module, and in addition, the output end of the display module is connected with the liquid crystal screen. The locking mechanism comprises a hollow first fixing rod, a hollow second fixing rod, a base. The lower end of the first fixing rod is connected with the base by a vertical rotating shaft in a hinged manner. The fingerprint signature electrical locking system is advantageous in that during concrete device operation, checking of fingerprint information is required for unlocking, and then wrong entrance in a live-line interval and changing of an operation sequence are prevented; and at the same time, the fingerprint information is adopted for setting locking or unlocking, and a problem of forgetting of unlocking tools is prevented, and a burden of a worker is relieved, and in addition, working efficiency is improved.