The invention relates to a power grid comprehensive information monitoring graph generation system and method, and the system comprises a user display module, a data interface module, a design module, a configuration module, and a file interface module. According to the invention, the system and method build a mapping relation library based on a large-screen overall design scheme and a graphic file, which are generated in an integrated manner, and a visual graph element assembly. The system and method can achieve the packaging and flexible configuration of the visual assembly, can iron out the defects that a large-screen graph design scheme of a conventional power grid monitoring system is lower in reusability and is difficult for later configuration and modification, can improve the utilization rate and the reusability of the assembly, and can improve the implementation efficiency of a project.