The invention relates to the field of oil field petroleum engineering, belongs to an anchoring and sealing integrated soluble ball seat for fracturing of large-scale volume fracturing transformation of a horizontal well, and solves the problem that the diameter of a preset working cylinder is reduced, so that after the ball seat dissolves, the situation that a well shaft is in full-bore cannot be realized, and the subsequent construction of a well is influenced. The anchoring and sealing integrated soluble ball seat consists of a setting pull rod (1), a setting push cylinder (2), profiled sealing pieces (3), an upper divided segment (4), a cross guiding body (5), anchoring slips (6), fixing pin bolts (7), a lower divided segment (8), a spring locking pin (9) and a protecting base (10). The anchoring and sealing integrated soluble ball seat disclosed by the invention has the advantages of being able to be anchored and sealed at any position in a sleeve pipe, high in pressure bearing capacity, soluble, free from series limit and the like, and after fracturing construction is performed, full-bore is realized at a high speed.