The invention belongs to the technical field of electric actuation mechanisms and particularly relates to a double hand wheel electric actuator. The double hand wheel electric actuator comprises a casing; an output shaft is vertically arranged in the casing; a worm gear is arranged in the middle of the output shaft in a sleeving manner; and a first hand wheel is arranged above the output shaft. The double hand wheel electric actuator further comprises a handle, a worm, a second hand wheel, a plug and a dustproof cover; the handle is used for controlling switching between an electric operation and a manual operation; the worm is horizontally arranged and is matched with the worm gear; one end of the worm is connected with a motor; the other end of the through the casing; a connecting sleeve for being connected with the worm is arranged at a mounting hole on the inner side of the second hand wheel in a connecting manner; the connecting sleeve is of a square inner hole structure for allowing the worm to penetrate through; the plug is detachably arranged at a mounting hole on the outer side of the second hand wheel; and the dustproof cover is arranged at the exposed end of the worm and can be detached. The double hand wheel electric actuator provided by the invention is simple, convenient and labor-saving in operation and is simple and reasonable in structure.